Cushing Syndrome: The Hormonal Condition Behind Amy Schumer’s Noticeably ‘Puffier’ Face Unveiled

Amy Schumer, the well-known comedian, recently shared with her fans that she has been diagnosed with a rare hormonal condition known as Cushing’s syndrome. This revelation came after a flurry of comments on social media about her looking different, especially following her appearance on “The Tonight Show with Jimmy Fallon.” Addressing the critical remarks, Schumer took to Instagram with a candid post, disclosing that she was dealing with endometriosis and other health issues, stressing the importance of women educating themselves about such diseases.

“You’re right it is puffier than normal right now I have endometriosis an auto immune disease that every woman should read about. There are some medical and hormonal things going on in my world right now but I’m okay,” wrote Schumer.

The conversation around her appearance, which ranged from concern to outright negativity, was what made Schumer realize that she needed to seek medical advice. Cushing’s syndrome, which Schumer was diagnosed with, results from high cortisol levels in the body. This “stress hormone” can cause symptoms like facial puffiness, weight gain, and muscle weakness, potentially leading to serious health problems including high blood pressure, diabetes, and bone loss over time. 

During a particularly busy period promoting the second season of her Hulu hit “Life and Beth,” Schumer underwent numerous medical tests, experiencing the stress of potentially not being there for her son’s future. However, discovering that her condition would resolve itself was, for Schumer, incredibly relieving news.

Unlike other cases where surgery might be necessary due to a tumor, Schumer’s Cushing’s syndrome was attributed to high-dose steroid injections. Although she has openly discussed her battle with endometriosis, which can be treated with steroids, it’s not specified if this was the reason for her treatments. Reducing steroid use can often reverse Cushing’s symptoms.

Schumer sheds light on the criticism women endure as their bodies undergo changes. Numerous social media remarks following her appearance on “The Tonight Show” were mocking and sexist. She used this moment to promote self-love and acceptance, urging women to embrace their bodies without feeling the need to justify their appearance to anyone.