Major medical emergencies are difficult to anticipate and prevent compared to the other dangers on this list. But one thing is certain: heart attacks, strokes, and sudden illnesses don’t care how far away you are from the nearest road. For this reason, if you take medications or have health concerns that could affect your ability to exercise in a remote environment, you should talk with your doctor before tackling a strenuous mountain hike. If they approve, ensure that a friend or family member is aware of your planned location and itinerary.