What started out as a one-night stand after meeting at a Seattle bar and ended with wedding vows. For fans of Grey’s Anatomy, there’s no question Meredith and Derek became the heartbeat of the show. Their chemistry leapt off the screen, carrying the viewers through all of breakups, reconciliations, professional rivalries, and family tragedies. They started as two ambitious surgeons and grew into partners raising a family amid chaos. Derek’s death obviously ended their time together, yet his presence shaped Meredith’s story for seasons afterward.
David “Jill” Jillefsky and Jack Barrett — Jack & Jill
This late-90s dramedy never reached the heights of Friends or Sex and the City, but its central couple deserved far more attention than they got. David, nicknamed Jill, and Jack had the kind of relationship that felt real: full of mixed signals, bad timing, and, of course, heartfelt rooftop confessions befitting of a show based in New York City. Unfortunately, Jack & Jill was axed after only two seasons, leaving fans to forever wonder how their story might have unfolded.
