Alexis Bledel and Vincent Kartheiser
Meeting up in 2012, she was a guest star on Mad Men, where she played as Beth Dawes, a woman who had an affair with Vincent’s character Pete Campbell. The relationship didn’t work on the film, but the two in real life worked out fine. They married in 2014 and had a son the following year.
Stephen Moyer and Anna Paquin

The two lovebirds met up on everyone’s favorite vampire sex show, True Blood. The two ended up getting married in 2010.
Natalie Portman and Benjamin Millepied
While not necessarily actors, Millepied worked closely with Portman seeing as he was the choreographer on Black Swan and she was a ballerina. The two had a son in 2011 and married in 2012.
Bradley Cooper and Zoe Saldana

Met on the set in 2011 filming The Words and went public in 2012. They split later that year.
Claire Danes and Hugh Dancy
Met on the set of Evening in 2006 and got married in 2009.